FALSE-NEGATIVE DENGUE CASES

False-negative Dengue Cases

Dear Editor, we would like to discuss on the recent publication on false-negative dengue cases. ACOSTA et al. reported that “Health care providers should therefore be aware of samples tested negative by NS1 antigen assays, especially when clinical symptoms and other laboratory data results show evidence of dengue infection”. In fact, the problem of false-negative in dengue diagnosis is an impor...

False-negative Dengue Cases in Roraima, Brazil: an Approach regarding the High Number of Negative Results by Ns1 Ag Kits

Serum samples from 150 NS1-negative (Platelia ELISA) patients presumptively diagnosed with dengue were analyzed by the TaqMan probed real-time reverse transcription PCR (TaqMan qRT-PCR) method. The qRT-PCR positive samples were tested for serotype by semi-nested RT-PCR and a qualitative immunochromatographic assay for IgG and IgM. Molecular detection methods showed 33 (22%) positive samples out...

Post dengue hair loss: low prevalence in Thai cases

False Negative Fecal Occult Blood Test: Prozone Effect

Dear editor, the fecal occult blood test is the presently widely used screening laboratory test for colorectal cancer. At present, the test is usually based on an immunological diagnostic principle (1, 2). A false positive fecal occult blood is common and widely mentioned in literature. Nevertheless, the false negative is little mentioned in the paper. Here, the authors discuss the issue of the...

Evaluation of inadequate, indeterminate, false-negative and false-positive cases in cytological examination for breast cancer according to histological type

BACKGROUND We previously investigated the current status of breast cytology cancer screening at seven institutes in our area of southern Fukuoka Prefecture, and found some differences in diagnostic accuracy among the institutions. In the present study, we evaluated the cases involved and noted possible reasons for their original cytological classification as inadequate, indeterminate, false-neg...